SHBG (Sex Hormone-Binding Globulin) – SHBG is a protein that binds sex hormones – especially testosterone and estradiol – and controls how much is free and active.
What SHBG measures
SHBG measures how much of your sex hormones are bound versus available. It helps interpret testosterone and estrogen results.
Typical ranges
Labs provide sex- and age-specific ranges. Reference ranges differ between laboratories and by age and sex, so always read your result against the range printed on your own report.
What high results can mean
Leaves less free hormone available; associated with aging, thyroid, or liver factors.
What low results can mean
Leaves more free hormone; associated with insulin resistance, obesity, or PCOS.
How the test is done
A blood sample; often measured with total testosterone to estimate free testosterone. At-home collection works well for this marker when the sample is processed by a certified lab.
FAQ
What is a normal SHBG level?
Labs provide sex- and age-specific ranges. Your ideal target depends on your age, sex, and health history, so review results with a clinician.
What does a high SHBG result mean?
Leaves less free hormone available; associated with aging, thyroid, or liver factors.
Can I test SHBG at home?
Yes. A blood sample; often measured with total testosterone to estimate free testosterone. An at-home sample processed by a certified lab gives reliable results.
This article is educational and not a substitute for medical advice. Discuss your results with a qualified clinician.